Human GI tract
5 important questions on Human GI tract
How and why are ubiota host-specific?
Monozygotic twins have high similarity: host-genotpye or shared environment in early life
Dollow's law of irreversibility: loss of methane production
Carnivore/omnivore/herbivore: codiversification, host phylogeny and diet
Different ubiota fullfill same functions: common core
Long-term diet: enterotypes
What are the main drivers of the different enterotypes?
Bacteroidetes, Prevotella, Ruminococus
What are characteristics of Inflammatory Bowel Disease (IBD)?
- chronic inflammatory response to ubiota
- relapses and remissions
- two types: UC (colon) and CD
- no cure, no known cause
- distinct ubiota composition, reduced diversity and less stable
- Higher grades + faster learning
- Never study anything twice
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What are the differences between conventional/-ized mice and germfree mice?
conventional/-ized mice have
1: higher body fat %
2: higher metabolic rate
3: lower calory intake
How do ubiota act upon obesity (4)?
1: suppression fasting-induced adipose factor (fiaf) -> triglyceride accumulation in adipocytes
2: inactivation AMPK -> supression fatty acid oxidation
3: signalling ubiota (LPS) -> promoting low-grade inflammatory state
4: production SCFAs: energy fuel; regulating transit time and bowel movement
The question on the page originate from the summary of the following study material:
- A unique study and practice tool
- Never study anything twice again
- Get the grades you hope for
- 100% sure, 100% understanding
