Introduction AMI

4 important questions on Introduction AMI

Immediate management of ACS

  • 12-lead ECG (within 5 minutes of arrival).
  • Oxygen via face mask or nasal cannula.
  • Venous access. Blood is drawn for cardiac biomarkers, biochemical and haematological work-up.
  • Sublingual nitroglycerin 0.4 mg (repeated once or twice as necessary) may have beneficial effects. Side effects include hypotensive reactions and a hypotensive bradycardic response (Bezold–Jarisch Reflex).
  • Analgesia. Often oxygen, nitroglycerin and lessening of anxiety by reassurance, are sufficient. If not, administer small incremental boluses of intravenous morphine (1–2 mg), repeated until pain is relieved.
  • Aspirin 160–325 mg should be chewed and swallowed on arrival.

What was the mortality reduction in the ISIS-2 study comparing Aspirin with placebo.

23 %

What kind of medicine is Clopidogrel and how does it work.

Clopidogrel, is a thienopyridine that blocks the platelet ADP receptor.
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Which dose of Clopidogrel of Prasugrel should be administerd initially

Clopidogrel 300-600mg
Prasugrel 60mg

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