Summary: Adaptive Myology

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  • Introduction

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  • What is the main difference between normal calf muscles and SCP calf muscles in the development of force?

    The SCP curve is shifted to the left and steeper.
  • Where is the sarcoplasmatic reticulum located?

    Just below the sarcolemma, around the myofibril.
  • Why is the A-band anisothrophic?

    Because it contains both myosin and actin.
  • What is the main effect of lengthening Nebulin on actin?

    It will increase the length of the actin filaments.
  • What happens to a sarcomere when you stretch it?

    • titin stretches
    • nebulin stretches
  • What should you keep in mind when measuring the sarcomere-force relationship?

    The different lengths of the different sarcomeres.
  • What do the normalized curves of the sliding filament theory give you for information?

    Mechanical properties.
  • What can you say about the velocity dependent properties of sarcomeres at different lengths?

    Velocity dependent properties of sarcomeres are the same at different lengths.
  • How can you explain the force-length relationship that shows exponential decline in force?

    The potentially different length distribution across the fiber.
  • How to optimally determine the force length relationship?

    • maximal activation
    • length normalization
    • no fatigue
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