Bioassays - Bioassays in food safety - Natural toxins
8 important questions on Bioassays - Bioassays in food safety - Natural toxins
What are the natural toxins we have to screen for?
- phytotoxins (eg phytoestrogens)
- mycotoxins
- marine biotoxins (fycotoxins)
What are the bioassays for phytotoxins?
- ER CALUX assay
- YES (Yeast Estrogen) assay
- ER-binding assay.
You can screen for activity and if it is present you can try to isolate the compound with chemical methods.
Why do they use bioassays for mycotoxins?
So a bioassay is selective and sensitive, has a hight throughput and therefore can be used for screening.
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What is a example bioassay for mycotoxins?
What is the bioassay for marine biotoxins (fycotoxins)?
What are the new methods for bioassays on biotoxins (fycotoxins)?
- Embryotic stem cell derived beating cardiomyocytes
- Multi-electrode array platform with rat cortices
- Neuro-2a cytoxicity (MTT) assay
- Elisa Assay
How does the embryotic stem cell derived beating cardiomyocytes work?
How does muti-electorde array platform with rat cortices work?
Method is sensitive enough to detect marine biotoxins in extracts form shellfish samples.
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