Bioassays - Promises and pitfalls of bioassays in food safety - Pitfalls
3 important questions on Bioassays - Promises and pitfalls of bioassays in food safety - Pitfalls
What is the pitfall in biosassays of false positives and negatives?
A false positive can be given by natural ingredients that also bind to certain receptors.
Especially important in dioxins since natural ingredients can also have this effect.
Especially important in dioxins since natural ingredients can also have this effect.
What is the pitfall in absence of ADME (Absorption, distribuiton, metabolism and excretion)?
The more siple the bioassay is the more it can lose it toxicological relevance. Because it misses the things that can happen in the body.
You dont have an interspecial difference factor with the non animal bioassays.
You dont have an interspecial difference factor with the non animal bioassays.
What is the pitfall of bioassays in low / different sensitivity?
Different bioassays have different sensitivity so hard to compare the data.
So to compare use the TEF concept so in a relative way.
So to compare use the TEF concept so in a relative way.
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