Bioassays - Bioassays in food safety - Environmental contaminants

4 important questions on Bioassays - Bioassays in food safety - Environmental contaminants

What are the environmental contaminants that we need to screen for?

Dioxins ans heavy methals.

What are the bioassays for Dioxins?

  • DR CALUS
Used for rapid high throughput screening. Only suspected samples to be analysed by expensive analytical techniques.


Dioxin binds to receptor. This makes that a protein which florises can be made. So by the florescence you can determine the amount of compound present.

On what are the cut off values for dioxin based?

They are based on the matrix of food. So different or fish and milk.
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What assay is used for heavy metals?

Traffic light assay.

  • 4 different strains with different treshold values
  • If you see a reaction occuring for 2 and not for the other 2 you know the concentration of contamination.  

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