Mass spectrometry - Ion Analyzers
7 important questions on Mass spectrometry - Ion Analyzers
What is a magnetic sector?
Molecules bend differently in a electromagnetic field due to there m/z ratio.
What is a quadrupole?
- The most used analyzers.
- Ion separates by moving in a constant electric field superimposed with an oscillating electric field. According to the frequency of oscillation, only certain m/z ratio will reach the detector. Varying the frequency will ensure a scan of all the ions.
- Limited resolution (about 2000) and limited range (usually not over 5000 m/z)
What is ion trap (IT)?
- Ions are «trapped» by several oscillating electric fields and selectively sent to the detector according to their m/z ratio.
- Today more and more substituted by «linear ion trap»
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What is time of flight (ToF)?
- Ions are “pushed” by an electric field in a tube where they drift until they reach the detector
- The time needed is proportional to their m/z ratio
What is Fourier transform ion cyclotron resonance (FT-ICR)?
- Ions rotate in a magnetic field inducing electric signals in detector plates.
- Frequency of rotation is proportional to their m/z ratio
- Incredibly high resolution (100000)
What is the triple quadrupole (QqQ)?
Multiple stage experiments with more than one analyzer are called MS/MS
For what do they use quadrupole-hexapole-ToF?
The question on the page originate from the summary of the following study material:
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