Fatigue, cognition, and mental effort

9 important questions on Fatigue, cognition, and mental effort

Is there difference in functioning on NP tests when low or high in fatigue?

No.

Do pt. or healthy participants perform worse in NP tests when fatigue plays a role?

Healthy participants

What tasks are more susceptible to fatigue?

Tasks that require more control of behavior. Cognitive fatigue induced by deterioration of executive control (ability to regulate perceptual and motor processes in order to respond in adaptive way to novel or changing task demands)
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What functions does fatigue influence?

Fatigue influences higher level executive control (flexibility, planning) and motor performance

Do  caffeine, naps and stimulants show improvements in level of fatigue and in who?

Caffeine, naps and stimulants all showed improvements on tests: only for healthy subjects

What is thought to be a problem when comparing healthy and clinical populations?

Not measuring the same thing when comparing healthy with clinical populations? Maybe ‘’sleepiness’’ and fatigue cannot be compared

What is thought to be underlying cause of mental fatigue with regards to functional imaging studies? Name an example.

Perception cognitive fatigue result of increased cerebral effort required to perform same amount of cognitive work. Mild TBI subjects require additional cerebral resources to compensate for processing inefficiencies

What are thought to be reasons of increase in cerebral activity that causes fatigue?

1.  Reason could be brain reorganizes in response to damage, left hemisphere forces right hemisphere to seek additional structures for compensation

2.  the brain needs extra resources (extra activation) to complete the task which was a routine or automatic before this overactivation leads to slower , less efficient, less accurate responses

Activation in what areas in the brain is associated with high and low fatigue?

Self-reported fatigue associated with frontal lobe and basal ganglia dysfunction and related to difficulties in motor programming and response execution. This could mean that there is an impaired interaction between cortical and subcortical functional systems

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