Post transcriptional gene control III - Regulation of eukaryotic mRNA degradation

4 important questions on Post transcriptional gene control III - Regulation of eukaryotic mRNA degradation

What is the process of deadenylation-independent mRNA decay ?

1. Edc3 and Rps28B complex bind 3'-UTR
2. Decapping
3. 5'-->3' decay by XRN1

What is the process of deadenylation-dependent mRNA 5'-3' decay?

1. Decapping by DCP1 and 2 copmlex
2. XRN1 nucelease activity

What is the process of deadenylation-dependent mRNA 3'-5' decay?

1. Exosome binds
2. Scavenger decapping
3. Degradation
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What is the process of endonuclease-mediated mRNA decay?

1. Endonuclease cuts mRNA
2. 3'-5' decay by exosome
3. 5'-3' decay by XRN1

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