Cell cycle I - Genetic dissection of the cell division cycel (cdc)

3 important questions on Cell cycle I - Genetic dissection of the cell division cycel (cdc)

Why are unicellular eukaryotes excellent organisms to analyse the cell cycle genetically?

They can be grown as haploid cells

What is the mutation in cdc mutants with short cells?

The mutated gene codes for inhibitors of cell division, premature cell division

What are 4 characterisitcs of s.pombe cdc2?

1. Gain of function --> short cells
2. Loss of function --> long cells
3. Identical to kinase of frog MPF
4. Similar to frog cyclin B

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