LE 2: Trancscriptional control of gene expression I - Prokaryotes - Response on environmental clues
3 important questions on LE 2: Trancscriptional control of gene expression I - Prokaryotes - Response on environmental clues
How does a one component regulatory module work? (3 steps)
1. Ligand binds cAMP activated protein
2. Conformational change
3. Facilitates binding to DNA
2. Conformational change
3. Facilitates binding to DNA
How does a two component regulatory system work? (4 steps)
1. Conformational change
2. Kinase domain activated
3. Active protein phosphorylates another protein
4. Protein binds regulatory DNA elements
2. Kinase domain activated
3. Active protein phosphorylates another protein
4. Protein binds regulatory DNA elements
Which one is more flexible and which one is faster? One component regulatory system or two component regulatory system?
One component regulatory system is faster
Two component regulatory system is more flexible
Two component regulatory system is more flexible
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