LE 4: Transcriptoinal control of gene expression III - Chromatin
3 important questions on LE 4: Transcriptoinal control of gene expression III - Chromatin
What is the effect of modifications of the histone tail of the nucleosome?
What is the process of heterochromatin formation at chromosome ends of S. Cerevisiae? (4 steps)
2. Tehtering of Sir3 and 4 recruits Sir2
3. Sir2 deacetylates adjacent histone tails
4. Deacetylated histone tails recruit more Sir3 and 4 and contribute to spreading
What is the process of heterochromatin formation at chromosome ends of S. Pombe? (3 steps)
2. HP1 binds to the mehtyl groups
3. HP1 oligomerizes this leads to chromatin compaction
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