WHY IS THERE AGE-RELATED BRAIN Aβ ACCUMULATION
5 important questions on WHY IS THERE AGE-RELATED BRAIN Aβ ACCUMULATION
Name the two mechanisms by which extracellular Amyloid beta can be eliminated
- degradation by IDE and/or NEP
- transport by RAGE and/or P-glycoprotein
What may be a mechanism by which amyloid beta can accumulate in the elderly?
APP cleavage is carefully balanced, what may happen in the elderly with the expression and function of a secretase and BACE1?
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What may be an underlying cause of increased BACE1 expression in the ederly?
How may exercise influence APP metabolism?
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