Single-gene inheritance - The chromosomal basis of single-gene inheritance patterns - Single-gene inheritance in haploids

7 important questions on Single-gene inheritance - The chromosomal basis of single-gene inheritance patterns - Single-gene inheritance in haploids

In the discussion so far, the evidence for the equal segregation of alleles in meiocytes of both plants and animals is indirect, based on the observation that crosses show the appropriate ratios of progeny expected under equal segregation. Recognize that the gametes in these studies (such as Mendel’s) must have come from many different meiocytes. However, in some organisms, their special life cycle allows the examination of the products of one single meiocyte. What are these organisms called?

Haploids

In fungi, there are simple forms of sexes, what are they called?

Mating types.
In S. cerevisiae, there are two mating types, and a successful cross can only occur between strains of different mating types.

In experimental genetics, the wild-type allele for any gene is generally designated by?

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When two cells of opposite mating type fuse, a diploid cell is formed, what does this cell become?

The meiocyte.

Replication and segregation of r + and r would give a tetrad of two meiotic products (spores) of genotype r + and two of r, all contained within a membranous sac. What is this membranous sac called?

An ascus.

If the four spores from one ascus are isolated (representing a tetrad of chromatids) and used to generate four yeast cultures, then equal segregation within one meiocyte is revealed directly as two white cultures and two red. If we analyzed the random spores from many meiocytes, we would find about ... percent red and ... percent white.

50/50

What are the two reasons for using haploids as model organisms instead of diploids?

  1. In haploids a cross requires the analysis of only one meiosis; in contrast, a diploid cross requires a consideration of meiosis in both the male and the female parent.
  2. In haploids, all alleles are expressed in the phenotype because there is no masking of recessives by dominant alleles on the other homolog.

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