Specific immunity - Formation of antigen-specific receptors on T- and B-cells
3 important questions on Specific immunity - Formation of antigen-specific receptors on T- and B-cells
There are four segments of gene involved in recoptor formation. What are these four segments?
1. Variable (V) regions
2. Diversity (D) regions
3. Joining (J) regions
4. Constant (C) regions
How does clonal diversity occure?
1. Multiplicity of all segment regions
2. Frameshift in basepairs leads to production of different aminoacid
3. Insert of nucleotides by enzyme deoxyribonucleotidytransferase.
What are the two forms of TCR?
A heterodimer of an α- and a β-chain; constant and variable domain
The other form has a γ- and δ-chain
The other form has a γ- and δ-chain
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