Summary: Animal Breeding And Genetics | WUR

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  • 2 . Defining breeding goal and basic steps in setting up a breeding program

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  • Stap 5 BP: Selection and mating. Wat is hier belangrijk om te weten?

    Selectie bepaalt je genetische vooruitgang
    Mating does NOT affect genetic improvement

  • 8 belangrijke begrippen

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  • Setting up a breeding program

    1. Definition of production system
    2. Definition of breeding goal
    3. Collection of information
    4. Determining selection criteria
    5. Selection and mating
    6. Dissemination
    7. Evaluation
  • Characteristics breeding goal

    1. Often consists of a combination of traits
    2. should ideally summarize all traits in a single criterion
    3. contains breeding values
    4. contains values to weight the triats
    5. should aim at the future
    6. contain economic and non-economic weights


    should consists of:
    - definition of the trait
    - desired direction
  • Genetic diversity can be measured by

    1. The number of alleles in a population -> the more alleles, the larger the genetic diversity
    2. the frequency of those alleles -> the more equal, the larger the diversity. 
  • Gain in genetic diversity

    1. Mutations -> A dominant mutation often results in mortality of the embryo
    2. immigration
  • Rate of inbreeding gives an indication of

    - the risk of inbreeding depression
    - the decrease in genetic diversity and room for adaptive capacity of the animals in response to an environmental change
    - maximum level is 1
  • Additive genetic relationship

    - reflects what proportion of the DNA two animals share because they have common ancestors
     - estimated using
    1. pedigrees
    2. genomic information (SNP markers)   
  • Acceptable rate of inbreeding

    - keep the rate of inbreeding below 1%, perferably below 0.5%
    - 1% means that homozygosity will increase with 1% per generation
  • Epistatic effects (I)

    - there are genes interacting with each other
    - one gene needs the products of another gene to come to expression resulting in gene-pathways
  • Dominance effect (D)

    - indicate the sum of dominance effects per gene
    - the expression of the gene itself depends on the allele combination of that gene 
    - two recessive genes will result in a different expression than one recessive and one dominant
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