Antenatal Care

18 important questions on Antenatal Care

Normal blood pressure changes in pregnancy

Falls in 2nd Trimester by 30/15mmHg (reduced vascular resistance)
Rises in 3rd trimester

Clinical Manifestations of Pre-eclampsia

Oedema
Proteinuria
Hypertension
Eclampsia
Liver damage
Clotting abnormality

Assessment of Protein in pre-eclampsia

Dipstick (1+ or 2+ quantify)
24hr collection <0.3g/24hrs
Protein:Creatinine ratio > 30mg/nmol
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Foetal complications in Gestational diabetes

Congenital abnormalities 3-4x more likely
Preterm labour in 10%
Birthweight increased (hyperinsulinaemia/fat deposition)
Polyhydramnios

Maternal Complications in Gestational diabetes

Pre-eclampsia more common
Diabeteic nephropathy
Retinopathy

Management of Pre-existing diabetes in pregnancy

HbA1c aim for less 7%
Visitis until 34 weeks fortnightly
Monitor foetus
Aspirin 75mg daily for 12 weeks to reduce risk of pre-eclampsia
Delivery by 39 weeks (c-section if exceeds 4kg)

Management of Gestational Diabetes

Diet
Metformin
Insulin if high

Respiratory changes in pregnancy

Tidal volume increases by 40% in pregnancy
RR stays the same
Asthma common in pregnancy

Renal changes in pregnancy

GFR increases 40%
Urea and creatinine levels decrease

Illegal Drugs and Pregancy

Opiates = IUGR; preterm; SIDs (can do methadone maintenance but not withdrawal). Neonates can have withdrawal symptoms

Cocaine = IUGR; placental abruption; teratogenic; Intellectual impairment

Ecstasy = teratogenic (cardiac defects and gastroschisis)

Benzodiazepines = facial clefts; neonatal hypotonia and withdrawal

Cannabis = IUGR and later development (hard to be sure as people tend to use more than just cannabis

Foetal alcohol syndrome

Facial abnormalities
IUGR
Abnormal or small brain
Developmental delay
> 18 units per day

Treatment for Anaemia in Pregnancy

Iron Deficiency Anaemia = 10% and then gets to depleted stores by term.
Folic acid can co-exist. Symptoms absent unless <9g/dL
Oral iron

Folic acid and vit B12 should be considered in macrocytic anaemia.

Management of non-viable intrauterine pregnancy

Expectant
Medical (prostaglandins)
Surgical

Sites of ectopic pregnancy

Fallopian Tube 95%
Ovary
Cervical
Cornual (where tubes and uterus meet)
Abdominal

Clinical Features of ectopic

Lower abdominal pain (initially colicky)
Dark vaginal bleeding
Amenorrhea in 4-10 weeks but may think vaginal bleed is period

Movement of uterus may cause pain
Cervical os closed

Intrauterine Growth Restriction

Foetus has failed to reach own growth potential

Ultrasound assessment of foetal growth

Doppler umbilical artery
Doppler waveforms of the foetal circulation
CTG

Abdominal wall defects

Exomphalos (partial extrusion of abdominal contents in a peritoneal sac)
Gastroschisis (free loops of bowel in the amniotic cavity)

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