Summary: Antigeen Presenttaie Quiz
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1 Quiz
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How many peptides are presented in how many MHC class I molecules on each cell in a healthy situation?
Thousands of peptides bound to and presented by 6 different MHC class 1 molecules -
A pathogeen is entering a wound in the skin and is taken up by dendritic cells. How do they migrate to the lymph nodes
Afferent lymph vessel -
What does an immature DC need to mature?
TLR signalling -
What signal given by dendritic cells in the lymph node leads to T cell deletion or anergy induction?
Signal 1 only (MHC-peptide complex) -
A CTL will not attack a healthy non infected cell (true or false)
True -
Some viruses try to escape the effector CD8+ T cell response directed to virally infected cells. What would be a possible pathway of these viruses to do this?
Inhibition of TAP function -
Is the CD8+ T cell response to the same influenza virus strain identical in each individual?
No , because different antigenic peptides from influenza virus will be presented in different HLA molecules in different individuals -
Which one does not instruct other cells for pathogen elimination?
CTL -
What happens to patients that have immunideficiency and have no CD4 + T helper cells?
They have deficient B cell responses and cannot raise antibody titers to vaccinations -
What is immunosurveillance and why is it important?
Tumor cell detection by immune cells via tumour antigen inducing elimination
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