Additives 1 and
4 important questions on Additives 1 and
How many additives in the world? How many allowed in EU?
- 350 in the EU 'E numbers'
- EU has the most strict regulations
- US no regulations
What is the most widely used additive E-numbers?
What are the most widely used preservatives in food?
- Sugar, salt
- gases (additives)
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How is the safety determined?
- Toxicity in biological model systems (cell lines)
- Toxicity in (a number of) test animals
- Determine the No Observed Adverse Effect Level (NOAEL) based on most sensitive comparable animal (50g/kg bw/day during whole life)
- Correction NOAEL for difference between man and animal
- Correction NOAEL for difference between people
- Corrected NOAL is ADI (Acceptable Daily Intake)
- Convert ADI to maximum dose in products, including naturally occurring concentrations
- Adjust maximum dose for certain population groups
- Exclude for certain population groups
The question on the page originate from the summary of the following study material:
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