Fungi - Fungal diseases
6 important questions on Fungi - Fungal diseases
Properties of superficial mycoses:
- Fungi do not cause a host cellular response
- 'infections' do not cause pathology
- patients only gets concerned of cosmetic reasons and not of discomfort
- generally affects stratum corneum (hoornlaag) of skin and hair
Properties of athelete's foot:
several different fungi and transmitted in moist environments (with people with bare feet)
Properties of subcutaneous mycoses:
- Infections involve deeper layers of the dermis and subcutaneous tissues
- formation of lesions (damage)
- remain localized or spreads directly via lymphatic system
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Properties of systemic mycoses:
True systemic mycoses:
- inhalation -> pulmonary infection -> dissemination
- caused by fungi existing in nature
- geographic distribution varies
- no evidence of transmission among humans and animals
- dimorphism: can have different shapes depending on environmental factors -> can grow in filamentous or yeast form
Opportunistic systemic mycoses
- any fungus in nature can cause opportunistic mycoses
- candidiasis causes nosocomial infections (=hospital infections)
- aspergillosis is the most deadly mold
- cryptococcosis
- zygomycosis
What causes higher susceptibility for mycoses?
- HIV
- malignancy and chemotherapy
- organ and bone marrow transplantation
- Neutropenia, corticosteroid therapy, immunosuppression, graft-versus-host disease (donor cells attack body)
Properties of saprolegnia (cotton wool)
need wet environments to complete its lifecycle, fatal if not treated
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