Biology of pathogens: Viruses
10 important questions on Biology of pathogens: Viruses
Examples of DNA viruses:
- Pox
- herpes
- adeno
- papilloma
Examples of RNA viruses:
- Polio
- HIV
- influenza
- corona
- rabies
- mumps
What factors cause general transmission?
- Abiotic environmental factors (wind, water)
- animal factors like mosquitoes and fleas
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What factors cause human to human transmission?
- Direct contact (survival best in body)
- indirect contact (survives hash environments)
- dropelts (pathogens do not survive outside host)
- airborne (pathogens are aerosolized)
- fecal-oral route (through contaminated water/food)
West Nile Virus transmission:
- 'Amplifier host' are birds, horses, humans are 'dead end' hosts.
- likelihood that mosquitos bite birds is higher and they will have a higher concentration in the blood than horses or people.
- Virus often goes away symptomless, in a few cases it escalates to west nile fever of west nile encephalitis (hersenontsteking)
West Nile Encephalitis:
- Inflammation of the brain, CNS, often caused by viral infection
- symptoms: fever, headache, vomiting, irritability
When was the new york outbreak of west nile fever? WNV
When was the resurgence (comeback) of WNV in the US and what caused it?
What are the 5 strategies for developing a vaccine for WNV?
- Killed vaccine (only for horses)
- subunit vaccine (based on proteins)
- live attenuated strain (not succesful)
- chimeric virus (yellow fecer virus vaccine with replaced prM and E genes
- DNA vacccines
What is usuto virus and when was the outbreak?
The question on the page originate from the summary of the following study material:
- A unique study and practice tool
- Never study anything twice again
- Get the grades you hope for
- 100% sure, 100% understanding
