Sex and the Brain

16 important questions on Sex and the Brain

Why is the hypothalamus important in terms of hormones?

It controls the levels of hormones in our body and this affects our behaviour

What is a genotype?

Genotype is the full set of genes that an organism possesses (different genes are organised into chromosomes)

What pair number are the sex chromosomes?

23
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What is the Mullerian inhibitory hormone?

It inhibits the formation of the Mullerian ducts and the Wolffian ducts are retained = this turns foetuses into males

If it wasn't for the Mullerian inhibitory hormone, all foetuses would result as female

When are androgens released? What does this lead to?

Pre natal and in the first week of post-natal - this leads to the development of the testes as well as changes in the brain (especially the hypothalamus) e.g. the female hypothalamus releases hormones cyclically, the male steadily 

Estradiol is important in masculanising male brains. Why does estradiol not masculanise females' brains?

Because estrogen is bound using alpha fetoprotein into an inactive form in both sexes. In male brains, testosterone is converted into estradiol by aramatase - this results in estradiol i.e. you need high levels of testosterone to begin with

What is meant by sexually dimorphic behaviour?

When animal behaviour differs between the sexes.

What happens when the female rat is ready to mate?

When a female rat is ready to mate, she displays behaviours such as hopping, darting, and ear wigging. Then she adopts a lordosis posture. This is mediated by the ventromedial region of the hypothalamus which has many estrogen receptors.

This prompts the male to mount the female and begin to mate, mediated by the preoptic area of the hypothalamus

What happens to the oestragen levels around ovulation?

Oestragen levels are at their highest around the time of ovulation = makes the chances of pregnancy high if the female has sex at this time.

What area of the brain stops males from mating when the suffer a lesion to it?

Lesions to the sex neurons in the hypothalamus (preoptic region)

When this happens the males continue to show interest in females e.g. monkeys with lesions to the hypothalamus will not mate with females but they will masturbate while watching them. i.e. their ability to cary out a sexual act is not limited; however, they do not want to copulate with a female

What experiment studied sexual motivation and mating?

Experiment - a male rat is required to press the bar to gain access to a receptive female who 'drops' in through a trap door

Result - a rat with lesions to the hypothalamus will continue to press the bar to gain access to the females but they do not copulate when the arrive. On the other hand a rat with a lesion to the amygdala shows no interest in accessing the females, but will copulate if they are placed in the cage.

hypothalamus = sexual behaviour
amygdala = motivation

What are 3 outcomes of lesions to the frontal lobe regarding sexual behaviour?

1. Can result in a loss of inhibition about sexual behaviour and a loss of interest in sexual behaviour

2. Can bring about erotomania - a condition in which they think the other person is in love with them

3. Lesions to the dorsolateral prefrontal cortex is likely to result in aggressive sexual behaviour

When is oxytocin released during childbirth? What cognitive effects does it have?

It is released during the final stages of childbirth, cognitive effects may promote pair bonding

What kinds of tests do women tend to perform better in and what type of tests do men perform better in? What evolutionary reasons are behind this? What neural evidence is behind this?

Women do better in verbal fluency tests
Men do better in spatial reasoning tests

Evolutionary reasons

Men have tended to range over larger territories than women and so needed greater spatial abilities. It can also be argued that women were left behind in social groups and thus were more likely to develop tools for social communication

Neural evidence

The frontal lobe and the corpus callosum is larger in women compared to men

Why do men tend to be more aggressive than women?

This is correlated with the levels of circulating androgens in the system which decrease the amount of serotonin release

What evidence shows that difference in brain structure reflects sexual orientation?

1. Gay women have asymmetric brains like straight men (geared to the right hemisphere)

2. Gay men have symmetric brains like straight women

3. The amygdala of straight women and gay men connect to areas of the brain that manifest mood, fear and anxiety

4. The amygdala of gay women and straight men connects more to the sensorimotor systems and striatum of the basil ganglia - much more action related response

5. The SCN (suprachiasmatic) is twice as large in gay men as heterosexual men

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