Cell-cell and cell-matrix adhesions
12 important questions on Cell-cell and cell-matrix adhesions
Which 2 types of junctions do you have?
Name a type of occluding junctions, and what adapter proteins does it use, and is it connected to the cytoskeleten?
Name a type of adherins junctions, their adapter proteins and the type of cytoskeleton they use.
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Name a type of anchoring junctions, adapter proteins they use and the type of cytoskeleton.
What is the function of a gap junction?
Whats the the difference between hemidesmosomes and desmosomes?
Name 2 types of adhesion molecules
What do integrins do? And how many do humans contain?
What happens during outside-in signaling?
1. Integrin binds to ECM
2. Bpart of integrin binds to talin
3. Talin binds to actin
What happens during inside-out signaling?
1. activation of talin
2. Binding talin to B-part integrin
3. Change ECM domain integrin
4. Integrin binds to ECM
During inside out signaling talin gets activated, what does this trigger?
Name a non-protein type of ECM and its function
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