Case 4; milk

10 important questions on Case 4; milk

What can you tell me about the oestrous cycle?

- cow's have an oestrous cycle of approx. 21 days (starts at puberty at approx. 8 months)
- when initiated, the cow is ready to be inseminated around the time of ovulation
- cycle can be divided into a luteal and a follicular phase

What can you tell me about the luteal phase?

- compromises a metestrus and a dioestrus
- starts with ovulation and last until the regression of the corpus luteum

What can you tell me about the follicular phase?

- compromises a proestrus and an oestrus
- defined as the period between the regression of a corpus luteum and ovulation
- at the end of follicular phase, the cow will be in oestrus
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What can you tell me about the corpus luteum?

- the structure that remains when a follicle has ruptured from an ovary during the previous ovulation
- it produces progesterone (P4), which functions to maintain an appropriate uterine endometrium for a potential embryo to develop in. The P4 concentrations increase during the luteal phase
- no fertilization: the corpus luteum will degenerate and stop producing P4. This allows another follicle to grow and rupture from an ovary under the influence of oestrogen (E2) during the follicular phase -> marks the next ovulation

In this schematic overview of the mammary gland, the organisation and its functioning are depicted. Name what happens at each number

1. Suckling results in the travelling of impulses to the hypothalamus through afferent nerves
2. These impulses stimulate nerves in the paracentricular nuclei. This causes the posterior lobe of the pituitary to release oxytocin
3. This oxytocin is delivered to the mammary gland through the blood
4. Which causes the myoepithelial cells around the alveolus to contract
5.  this contraction will release milk out of each individual; alveolus into small ducts and then into larger ducts. When the milk enters the larger ducts and the gland cistern, the neonate can drink from it (or be removed via milking the cow)

What can you tell me about the dry period of a cow?

- it comprosis approx. 40-60 days
- during this period, there is time for the mammary tissue of the dairy cow to involute
- this involution reflects the recovery and development of new epithelial cells
-> a dry period positively contributes to the proliferation of mammary gland epithelial cells
- for subsequent lactation, this proliferation contributes to max milk, protein and fat yields

What can you tell me about Negative energy balance (NEB)?

- results from early lactation in which the high milk energy output is not matched with sufficient energy from feed intake
- while the dry matter intake is decreased in the transition period, the milk production increases during early lactation, resulting inn an energy deficit
- if NEB persist cerrverrely, it can affect rreprroductivity and immunity, resulting in an increased culling rate

What are the negative effects of shortening or omitting the dry period?

1. Will prevent the mammarry gland from fulfilling proliferation -> decreased milk production in subsequent lactation
2. Difference in milk component levels
3. The production loss, with 0 days dry period, is lower for multiparous cows compared to primiparous cows. The production loss, with shorter dry period, is lower for primiparous cows

What can you tell me about ketosis in cows?

- a disorder related to the negative energy balance
- A negative energy balance is a result of too little energy intake to account for the energy needed for milk production
- results in low blood glucose levels and high levels of ketone bodies in the blood -> These ketone bodies can leak into the urine or milk, which will lead to loss of milk quality
- cows with energy shortage in their feed, will mobilise fat from their body, which results in a higher fat level in the milk they produce

- cows suffering will have decreased appetite

What can you tell me about milk fever in cows?

- the calcium concentrations in blood and plasma are decreased
- when this happens, calcium from the bones is depleted to replete the levels in the blood -> these processes take some time, which leads to a calcium shortage

The question on the page originate from the summary of the following study material:

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