Case 9; immunology
10 important questions on Case 9; immunology
What can you tell me about the prreventive measure "feed"?
- First instance -> the innate/congenital barriers of the animal are then in a position to withstand intrusion, if this does not work the animal has adequate reserves to build up its immunity rapidly and effectively
- Second instance -> nutrition plays an important role in the occurrence and remedying of metabolic diseases.
What can you tell me about the preventive measure "housing"
- housing system can raise the risk of infection by promoting (in)direct contact between animals, in this way, increasing the risk of the transmission of infectious pathogens
What can you tell me about the preventive measure "cleaning and decontaminating"
- hygiene, decontamination, disinfection
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What can you tell me about the preventive measure "isolation"
What can you tell me about the preventive measure "vaccination"
-> animal then builds up active immunity very specifically to counter the actual pathogen
- vaccination should occur in the pre-pathogenic phase
What can you tell me about epidemiological research?
- the effects of possible prevention and intervention measures are quantified
- initial step is to find factors that may be relevant by means of risk factor research, after which the transmission is modelled and important parameters are estimated for these models from field data and experiments
What can you tell me about the neuro-endocrine regulation? (Aspecific)
- pathogens are also a stress factor, wich generate a stress response as well as an immune response
- adaptation to climate factors occur via two mechanisms: the general stress response and an individual mechanism to maintain body temperature
What can you tell me about phagotosis? (Aspecific)
- certain white blood cells (the neutrophil granulocyte and the macrophages) are able to absorb foreign material and to break them down internally -> occur in blood and lymph, and can move to location of infection
- another function of macrophages -> can present antigens in order to generate a specific immune response
What are the two important forms of the innate/ccongenital immunological system?
2. Enzymes present in blood -> can destroy the infectious particles via a cascade
What can you tell me about specific immune response?
- it depends on the phagocytosis activity of the macrophages, because the alien material processed first has to be offered by the macrophages to the T- and B-lymphocytes before these carry out the immune response
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