Summary: Biomolecules At Work

Read the summary and the most important questions on Biomolecules at work

• 1 Lecture 1

• 1.1 mitosis and meiosis

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• Which one contributes to genetic variation, mitosis or meiosis?

  Meiosis

• 1.2 single gene abnormalities

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• What is X-linked recessive?

  1 mutant allele, son is affected, daughter is carrier

• What is cytoplasmic inheritance?

  Progeny is the same phenotype as mother

• 1.3 chromosomal abnormalities

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• What is aberrant euploidy?

  Whole chromosome set is numerically mutated

• 1.4 pedigree analysis

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• Which mode of inheritance corresponds to the pedigree?

  X-linked dominant

• 2 Lecture 2

• 2.2 linkage analysis

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• Are the genes in the picture in coupling, in repulsion or not linked at all?

  In repulsion

• In what way can linked genes be separated form eachother to form recombinants?

  Crossovers

• 2.3 linkage analysis trihybrid

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• How can you deduce the genotypes of the original parents the heterozygous testcross parent?

  Use classes without crossovers to deduce heterozygous testcross parent. Form this deduce the original parent.

• How can you determine the non-combinant and double crossover classes?

  Non-recombinant is the largest, double crossover is the smallest

• 2.4 markers

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• How is the variation at the marker locus called?

  Polymorphism