Microbial Infection and Pathogenesis - Genetics of Virulence and the Compromised Host
5 important questions on Microbial Infection and Pathogenesis - Genetics of Virulence and the Compromised Host
Define virulence and explain how it can be encoded by both chromosomal genes and mobile genetic elements.
Describe the significance of Salmonella pathogenicity islands (SPI1 and SPI2) in the context of virulence.
Explain how plasmids contribute to the transfer of virulence factors in Salmonella and other enteric bacteria.
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What is virulence attenuation, and why is it valuable in vaccine development?
Discuss the concept of compromised hosts and provide examples of factors that can compromise host resistance.
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