Microbial interactions with humans - pathogenesis - Pathogenicity and virulence

5 important questions on Microbial interactions with humans - pathogenesis - Pathogenicity and virulence

How do you call a pathogen that causes disease onley in the absence of the normal host resistance?

An opportunistic pathogen

How do you call the measure of pathogenicity and it's relative ability to cause disease?

The virulence

How do you call it when the virulence of pathogens decreases or is even completely lost.

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What does adherence mean in the medical microbiology?

The ability of a microorganism to attach to a cell surface

How does microbial pathogenesis work in a 7 step-plan:

  1. Exposure ( to pathogenesis)
  2. aderence (to skin or mucosa)
  3. invasion (through epithelium)
  4. infection (growth and production of virulence factors and toxins)
  5. toxicity (effects are local or systemic)
  6. Invasiveness (further growth at origional and distant sites)
  7. tissue damage / disease

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