Metabolic regulation - DNA-binding proteins

4 important questions on Metabolic regulation - DNA-binding proteins

Depending on whether the protein-nucleic acid interactions attaches anywhere along the nucleic acid or binds to a specific site. The proteins are ....

Specific or non-specific

Because of it's size what is the major site of protein binding on DNA

The major groove

DNA-binding proteins in both prokaryotes and eukaryotes possess several classes of protein domains that are critical for proper binding to DNA. What is one of the most common structures?

The helix-turn-helix
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Name the two helixes by name and give their function.

  1. Recognition helix (interacts with DNA)
  2. stabilizing helix (stabilizes the first helix by acting hydrophobic)

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