Metabolic regulation - negative control: repression and induction

7 important questions on Metabolic regulation - negative control: repression and induction

Name two simple forms of regulation that govern negative controle in gene expression. (on the level of transcription)

  1. Repression
  2. induction

Explain enzyme repression (a negitive controle of transcription)

Enzymes only synthesize if the product is absent. An excess of this product decreases the synthesis of these enzymes

Why is it that in bacteria in most cases the final product of a particular biosynthetic pathway represses the enzymes of the pathway?

This ensures that the organism does not waste energy and nutri:ents synthesizing unneeded enzymes
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What is the opposite concept of enzyme repression? In negative transcription controle

Induction

Which 2 small molecules are collectively called effectors?

  1. Inducer
  2. corepressor

How is it called if the conformation of a repressor protein is altered when the affector molecule binds to it?

The repressor protein is allostetic

What is the role of a repressor?

Stop transcription

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