RNA sequencing - GL Mutational signatures in cancer (Ruben van Boxtel)

3 important questions on RNA sequencing - GL Mutational signatures in cancer (Ruben van Boxtel)

Mutational processes leave a characteristic footprint consisting of?

  • Mutation type
  • Direct sequence context
  • Genomic distribution

How can a mutational process be identified?

By comparing to known signatures

The presence of a specific signature may be predictive for?

Treatment, predisposition, and cause of cancer

The question on the page originate from the summary of the following study material:

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