Summary: Case 2 Foie Gras
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1 How does the liver normally function? The role of the liver
This is a preview. There are 10 more flashcards available for chapter 1
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What are the main functions of the liver?
The main functions of the liver are:- Main storage of glucose (glycogen)
- Insulin and glucagon control
- Regulate release and uptake of glucose
- Fat metabolism
- Synthesis of bile (stored in gallbladder)
- Detoxifying blood
- Breakdown hemoglobin
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What enzyme is used for alcohol breakdown?
2e1 is the enzyme used for alcohol breakdown. -
Whicht enzyme is used for detoxification?
Cyt P450 is the enzyme used for detoxification. -
What are the different GLUT receptors and where are they used for what?
GLUT2 --> glucose in liverGLUT4 --> glucose in muscleGLUT5 --> fructose -
How is cholesterol transported into the cell?
Cholesterol is a hydrophobic molecule, so it needs to be carried via chylomicron, LDL, HDL (lipoproteins). -
What is different in the lipoproteins in MetS?
In MetS there is:- low HDL
- high LDL
There is a lot of cholesterol in the arteries. -
What is the function of fatty acids?
Functions of fatty acids:- cell membrane component
- energy
- precursor for some hormones
- post-translational modifications
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What does the density say about a lipoprotein?
The density of a lipoprotein says something about the relationship between cholesterol and protein amounts (ratio). -
Which lipoprotein transports from organs to liver?
HDL transports from organs to liver. -
What is the effect of a receptor interaction in LDL and HDL?
Due to a receptor interaction LDL and HDL can transform into each other.
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