What are the dietary influences on fatty liver development?

3 important questions on What are the dietary influences on fatty liver development?

What is the influence of frustose ingestion on NAFLD?

Fructose ingestion causes:
  • lower steatosis
  • higher fibrosis
  • more lipogenesis than with glucose intake (fructose can not be stored (glucose can) --> fructose is converted to fat)
  • increased de novo lipogenesis
  • increased LDL secretion
  • hypertriglyceamia

What does alcohol intake do?

Alcohol intake induces ROS and induces enzymes.

What is the role of cholesterol in the development of fatty liver?

Cholesterol can be stored as fat in the liver (the main storage of cholesterol is in adipocytes, in and around skeletal muscle and heart muscle)

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