What adipokines are secreted in the MetS? Which are increased, which are decreased? - Apelin
3 important questions on What adipokines are secreted in the MetS? Which are increased, which are decreased? - Apelin
When do apelin levels increase?
What is the response to apelin?
- endothelium-dependent vasodilatation
- lowers blood pressure (in rats, via pathways...)
What are the effects of treatment with apelin?
- diminishing of the formation of aortic aneurysms
- reduce macrophage infiltration
- lower the production of proinflammatory cytokines and chemokines
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