Function measurement - Filtration barrier
3 important questions on Function measurement - Filtration barrier
What is the filtration barrier
Barriers for a molecule to pass when it's filtrated in the glomerular capillaries. They prevent the filtration of bigger molecules form the plasma.
Glomerular endothelial cells
Glomerular capillaries are fenestrated capillaries (without diaphragm). The pores are small enough to prevent blood cells from leaving the capillary. The negatively charges proteins on the pore surfaces also help repel negatively charged plasma proteins.
Epithelium of Bowman's capsule
Podocytes = the portion of the capsule epithelium that surround each glomerular capillary. They have long cytoplasmic extensions called foot processes that extend form the main cell body.
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