Metoprolol
3 important questions on Metoprolol
What is the working mechanism of Metoprolol?
Metoprolol is a cardioselective beta-1-adrenergic blocking agent, which has an antagonistic effect on the beta-1-adrenergic receptors in the hear, thereby reducing blood pressure.
Why should patients that suffered from cardiogenic shock not be treated with Metoprolol?
Metoprolol's effects result in decreased heart rate, cardiac output and blood pressure, which may have a synergetic effect in combination with patients with inadequate circulation.
Why should Metoprolol not be taken in combination with calcium channel blockers?
The combination of Metoprolol with calcium channel blockers may increase the effect of the beta-blockers on the heart rate, blood pressure, cardiac contractility and atrioventricular conduction, which may lead to cardiac arrest.
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