Fluoxetine
3 important questions on Fluoxetine
How may fluotexine drug treatment lead to the side-effect of serotonin syndrome?
Fluoxetine blocks the reuptake of serotonin and stimulates the synaptic serotonin receptors, which may lead to accumulation of serotonin.
Why should Fluotexine not be combined with drugs that are also extensive plasma protein binders?
In this case, competition for binding place may occur, leading to more unbound fraction of drug, which may cause stronger pharmacological effects.
Why should patients with liver diseases receive a lower frequent dose of Fluotexine?
Fluoxetine is metabolized via the liver to the active compound norfluoxetine and is partly eliminated via the liver.
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