Innate Immune System - Complement

4 important questions on Innate Immune System - Complement

Name 5 examples of complement factors

  1. fibrinogen
  2. haptoglobin
  3. mannan-binding lectin
  4. serum amyloid A
  5. C-reactive protein

Name 3 functions of the complement system:

  • Rid the body of antibody coated antigens
  • Contribute to inflammation
  • Destroys bacteria

How does the a protein start to work?

It needs to be activated (by antibody eg). Often C3 is the first to be activated and then a complement cascade starts
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What is the end product of a complement cascade?

The MAC (membrane attack complex), which punctures through the cell membrane.

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