Cell cycle (van Weerink)
35 important questions on Cell cycle (van Weerink)
Why do cells divide?
- Wound healing
- Organ maintenance
Which phases happen during the interphase?
- G1 phase
- S phase
- G2 phase
What is the function of the cell-cycle control system?
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How are DNA replication, mitosis, and cytokinesis regulated or initiated?
Which proteins carry out dephosphorylation?
What is the function of Cdks and cyclin?
What is the function of M cyclin? Which cyclin is an M cyclin?
Cyclin B is an M cyclin.
What is the function of G1 cyclin? Which cyclins are G1 cyclins?
Cyclin D is a G1 cyclin.
What are the three checkpoints of the cell cycle? And what happens at these points?
- G1-S: It is checked if the external factors are OK for cell division and if the DNA is undamaged.
- G2-M: It is checked if the DNA is duplicated correctly
- M metaphase-anaphase: It is checked if the chromosomes are correctly attached to the spindles
How are Cdks returned to their inactive state?
What triggers the abrupt activation of cyclin-Cdk complexes?
How can the activity of a cyclin-Cdk complex be blocked?
How is the DNA prepared for duplication in the G1 phase?
How is DNA duplicated in the S phase?
What process prevents re-replication of the DNA?
What is the process of the checkpoint from the G2 to the M phase?
How are chromosomes split over daughter cells?
What is one of the function of M cyclin to proceed from the G2 to the M phase?
What is the function of condensin?
What is the role of duplicating centrioles?
What does the contractile ring consist of?
What makes that the nuclear envelope disappears and is re-formed?
How are chromosomes separated by the movement of microtubules during the anaphase?
How are chromosomes separated by APC/C?
What triggers cytokinesis?
What is the final contact between the two cells?
What are the critical cytoskeletal filaments during mitosis and cytokinesis?
Cytokinesis: actin
What is wrong with syndactyly patients?
What prevents cytochrome C release from mitochondria?
What can cytochrome C do?
What can block apoptosis?
External signals can stimulate apoptosis by activating a set of cell-surface receptors known as?
What is the metaphase-anaphase checkpoint?
What is the function of APC/C?
What is the process of cytokinesis?
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