Summary: Cellular Function 3: Carcinogenesis
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1.27 cell structure 3: carcinogenesis
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the process where cancer develops
carcinogenesis -
cell goes through event that causes DNA to be damaged or mutate
initiation -
involves the mutated cell's exposure to factors that promote growth
promotion -
when the tumor invades, metastasizes, and becomes drug resistant
progression -
activate cell division and influence embryonic development
oncogenes -
cell growth regulator; edits and repairs
p53 -
found in 30% of women who get breast cancer
HER2 -
host and environmental carcinogens
chemical carcinogens
human carcinogens
heredity
hormones
immunologic defects
radiation
oncogenic viruses -
standing consistently too close to the microwave is an example
nonionizing radiation -
varies from living for one year to eight hours
injured cell
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