Epidemiology atherosclerosis driven disease

13 important questions on Epidemiology atherosclerosis driven disease

Which countries most VCD death and why?

China/India
- Large populations
- Increase CV risk factors
- Demographic change towards older

Countries Europe low CVD risk?

Spain, Italy, France

Most important risk factors CVD?

Age
male Sex

Minor:

Smoking
high cholesterol
Physical inactivity
Alcohol abuse
Hypertension
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Men/women ratio CVD death?

Differs between countries. More male. More older women. So many women with CVD

Relation risk factor/risk?

J-shaped

Alcohol consumption and CVD risk?

2 glasses no risk -> higher risk other disease though

How rapid risk factors affect CVD mortality rate?

Very rapid. Migrant Japan -> US higher risk

Non invasively measure atheroscl.?

measuring plaque carotid. systemic atherosclerosis

Most powerful measurement cardiac death?

Calcium in coronaries

Cause of sudden rise carotid thickness in post menopausal women?

Asymptomatic intra wall haemorrages

Trigger factors MI?

Circadian: monday morning
Aspirin -> no circadian variation -> something to do with platelets??
Stress: football / earthquake

Pro en contra medication?

Pro:

men and women
Effective
Young/old

Contra:

Acces
Adherence
Side effects

Population improvements replace interventions?

No, huge potential and highly cost effective health gains

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