Alzheimer's disease - Introduction

3 important questions on Alzheimer's disease - Introduction

Which 2 factors play a role in the rapid increase of Alzheimer's or related dementia over the next few decades? (double ageing)

  1. Changing demographic structure
  2. increased life expectancy

What are a few of the risk factors for Alzheimer's disease?

  • Age
  • genetic predisposition
    • mutations APP, PS-1 and PS-2
    • APOE gene
  • vascular risk factors
    • hypertension, diabetes and smoking

Which core clinical criteria of dementia are named in the book when diagnosing Alzheimer's?

  • Memory impairment
  • aphasia
  • apraxia
  • agnosia
  • impairment executive functions
  • distinct deterioration compared to former level of functioning which poses major problems in daily functioning

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