Molecular mechanisms of learning and memory
24 important questions on Molecular mechanisms of learning and memory
Where in the brain is nondeclarative memory mediated?
Nondeclarative memory can be dividen in associative and nonassociative memory
nonasscociative: habituation and sensitization
Research conducted instrumental learning on the Aplysia. They found that sensory/motor neurons become habituated
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Research conducted instrumental learning on the Aplysia, they found that there is habituation at the presynaptic/postsynaptic level due to ....-channels becoming less-sensitive
Describe the presynaptic modification of the stimulation of the L29 neuron
If bot US and CS reach the motor neuron, what happens?
Of which three layers exists the cortex?
From which two fibres gets the Purkinje cell input?
What is the pathway of receiving information for the climbing fibre?
What is the pathway of receiving information for the Purkinje cells?
How responds the Purkinje cell upon stimulation by both parallel and climbing fibres?
Which three synapses lie in the HC?
How is hippocampal LTP achieved?
What is co-operativity in synapses?
What is spatial summation?
Describe the process of hippocampal LTP
What does a tetanus stimulation to HC LTP?
What will happen if you stimulate synapses with a low frequency? Describe how.
What does scaffold protein PSD-95 with AMPA?
What does LTP to PSD-95?
Why does phosphorylation for long-term memory not work?
2. Protein molecules are not permanent (they are constantly replaced)
Of which exist the 10 subunits of CAMKII?
How does autophosphorylation of CAMKII work and what does it do?
What do you need for permanent LTP?
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