Summary: Colleges
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1 Lecture 1 - CH1
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How can you get genetic improvement of an animal?
- Artificial selection of the best animals
- Natural selection -
How is an animal genetically improved with artificial selection of the best animals?
- Increase in frequency of favourable alleles
- Next generation is better than current generation -
2 Lecture 2 - CH2
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How do you determine te traits in a breeding goal?
Divide them in economic and non-economic -
What are other aspects to consider in a breeding goal?
- Ethical aspects
- Carbon footprint
- Competitive position of breeding program -
3 Lecture 3 - CH4
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What is the aim of collecting information?
- To be able to uniquely identify individuals
- To get an accurate impression of the performance -
Why are semen and oocytes not preferred as source of DNA?
Potentially large differences in DNA between cells due to meiosis -
What are genetic markers used for?
- Parentage testing
- Pedigree reconstruction
- Estimate biodiversity
- Estimate breeding value of animals
- Find genes (and use for genetic testing) -
5 Lecture 5 - CH7
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What is a heritable disorder?
- Often monegenic
- Often recessive inheritance
- Anything from little or no disomfort to lethal
- In some cases occur in multiple species -
What if a recessive disorder is lethal?
Prenatal mortalilty: no homozygous recessives born
Occurs fairly often: early abortions, prolonged non-return interval -
What is the procedure for genome wide studies?
1 Genotype many parents and their offspring
2 For very many SNP markers, or even sequence info
3 Look for absence of one of the homozygotes
4 Test for deviation from H-W
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