Biological embedding

22 important questions on Biological embedding

What is biological embedding

when experiences get under the skin and alter human biological processes. These differences are stable and long-term; and can influence health, well-being, cognition etc.
Why is this interesting? It is important to increase our understanding of biological mechanism involved because this will
- Facilitate the study of possible adverse outcomes and
- Contribute to developing strategies to prevent these outcomes (chances)


What do you remember about prenatal stress and its associations with infant outcomes?

Exposure to live events, child outcomes
- More ADHD symptoms
- More behavior problems, internalizing, externalizing and psychiatric problems
Exposure to natural disasters
- Less motor development
- Less cognitive development
- More negative affectivity

What is in the mother's milk

- bacteria
- minerals
- nutrients
- fats
- hormones
- immune factors
- HMO's
- cells of the mother, including stem cells
- vitamines
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Prenatal stress and child HPA axis; study examples

- Altered infant stress reactivity to novel stressors
- Altered infant stress reactivity to repeated stressors (habituated situations > children with high stress mothers have difficulty with this)
- Higher stress mother > higher cortisol levels children till 6 years

Epigenetic changes can be found in different body parts, including the brain. In one study we looked at the brain

- 3 groups; suicide, accident, control group
- Suicide; history of abuse or something in later adulthood


RESULT: much more glucocorticoids in persons who commit suicide or had history of being abused.  

False or true

self-regulation baby in bath by sucking on their hand

True1

What are developmental tasks and typical regulations problems for age 0-3 months

Developmental tasks;
- eating; coordinated sucking
- activity; sleeping vs being awake, being attentive and calm when awake
- energy; temperature

typical regulation problems
excessive crying, sleeping problems, feeding problems

What are the developmental tasks during 3-7 months old

Developmental tasks;
- eating; solid food, adaption to a new way of feeding, new tastes and textures
- activity; sleep through the night
- attention; looking and looking away during exploration and interactions

regulation problems;
sleeping problems, restlessness, overly sensitive, feeding problems

What are the developmental tasks and regulation problems during 7-9 months and up

Motor system; start of locomotion
attachment; balance between closeness with parent and exploring the environment, dealing with strangers

regulation problems;
extreme stranger anxiety, seperation anxiety, little exploration behavior

What are the intuitive caregiving competences

- Intuitive parenting
- Reading the infant’s signals and interacting in a sensitive manner.
- Infant directed speech; we adapt to infant with our speech, more variety in speech. Baby’s pay more attention to infant directed speech, repetition

What are parental risk factors

- Prenatal: Psychological problems during pregnancy (anxiety, depression)
- Perinatal; complications during birth, traumatic birth experience
- Postnatal; relationship problems, social isolation, chronic illness


Feeding problems, what happens with caregiver and what happens with the child

è Suboptimal alignment between caregiver and baby
è Caregiver might become more controlling
è Little attention for and acknowledge of subtle signals by the infant
è Tensed atmosphere
è Negative feedback
è Change to non-age

The child
è Constant rejection of food
è Baby responds in a negative way turns ways head
è Some infants or toddlers look for distraction and allow feeding only by the way
è Duration of the meal when/time differ

Infant factors in the emergence of feeding problems

- Medical problems
- Regulation problems
- Neuro-motor en oral sensory problems
- Traumatic experience
- Acceptance of new food only after repeated exposure

Caregiver factors in the emergence of feeding problems

- Problems during pregnancy and after birth
Fear of losing baby
- Psycho-social problems during pregnancy and postpartal period
- Little experience in dealing with young children
- Own eating problems (anorexia, boulimia, dieting)

What is video interaction guidance (feeding problems)

- if contact with caregiver does not go well naturally, videoimages can help to reinstall the contact

- practitioner watches video footage of an everyday interaction together with parents

- emphasis on positive moments
- identification of positive and negative parent behavior

Case of chayenne in video interaction guidance

Conflict about control, overall positive relationship between child and mother. Child wants to eat independently

Could gut microbes be affecting psychological stress levels

- Exposure to certain kinds of microbes had dramatic effects on brain chemical levels

- While germfree mice were more affected by certain kinds of acute stress (like restraint), they were less anxious about other kinds of stress, like being placed in a new environment

- Mice without a microbiome aren’t always more sensitive to stress

- Exposing germfree mice to microbiomes of other mice could influence their behavior

- Behavioral changes correspond to an increase in BDNF protein

CONCLUSION: so the microbiome does affect the brain!

Give a summary of video - mothers milk

Mother’s milk feed the microbiomes that are colonizing the infant’s intestinal tract. Milk provides immunofactors that help fight pathogens and mother’s milk provides hormones that signal to the infant’s body. Know little about mother’s milk > little research.
Mother’s do breastfeed, but do not reach their breastfeed goals. This is a problem; increasingly common medical conditions like obesity, endocrine disorders and preterm birth all can disrupt the underlying biology of lactation.
Cannot be provided in US because of no paid parental verlof.

Give a summary of the incredible years video

- training for parents and teachers to support them in their education of their children

- goal; give caregivers tools to deal with difficult child behavior

- trainings in groups, weekly meetings; information discussion of problems situations, exercises role play and video fragments

- topics; playing with your child, praise and reward, putting boundaries, dealing with unwanted behaviors

- enhancing sensitive interactions - building positive relationships
praising positive behavior, ignoring negative behavior

Goal of incredible years intervention

Cope with frustrations; important to find support
stay consistent and predictable in repsonse

Intervention: practicing techniques with other parents of child with ASD

-  Weekly class, also roleplaying with other parents - Videos with parenting describing play in a form of coaching

- Child-directed play as a teaching situation, social interaction

Different aspects of the ASD parent intervention

- Build language development (increasing vocabulary)

- Social coaching

- Emotional coaching (e.g. by reading books; looking at the facial expressions)

- Persistence coaching (persisting in kind of difficult activities) - Emotional self-regulation (by giving encouragement, talking about how to regulate it)

- Using pretend play (by playing with and talking to stuffed animals)

- Sensory routines (e.g. running, jumping when mad)

- Managing misbehavior (ignoring in the right situation; differential attention)

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