Sublethal effects

8 important questions on Sublethal effects

What is the definition of sublethal effects & how can sub-lethal effects lead to ecological mortality? Moreover, what 4 kinds of physiological processes change due to sublethal exposure?

Definition: Effects occuring at concentrations or doses below those causing death, but do cause harm to the organism. Sublethal effects may affect organisms in their fitness for survival, which could lead to ecological mortality as the affected organisms can't compete/survive anymore in their ecosystem due to the sublethal effects.

Affected physiological processes:
1. Growth
2. Reproduction
3. Behavior
4. Development

What is the difference between an LC50 graph and an EC50 graph

LC50 represents a graph that relates the toxicant concentration with the mortality rate of a group of species. From this graph, the Lethal concentration of the toxicant at which 50% of the group dies (LC50) can be deluded.

An EC50 graph represents a graph that relates the toxicant concentration with the affected physiological processes rate of a group of species. From this graph, the sublethal concentration of a toxicant at which 50% of a certain physiological process is affected can be deluded.

What is meant with teratology and what four effects can a Teratogen have and in which 5 ways can a Teratogen act to realize the effects?

Teratology indicates that a toxicant (in this case a teratogen) causes adverse effects on the embryo or fetus (larvae are also considered as embryonal effects).

4 Effects on Embryo or Fetus:
1. Embryo lethality
2. Anatomical malformation
3. Functional deficiencies
4. Slowed growth

5 Ways Teratogens act by interfering with:
1. Genomic imprinting.
2. Disrupting mitosis.
3. Interfering with transcription and translation.
4. Inter- & Intracellular signaling.
5. Disturbing metabolism.
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What is the Teratogenic index (TI) and what does a low or high TI indicate?

The Teratogenic index that is calculated by dividing the LC50 with the TC50 (which is the concentration at which 50% of the embryo malfunctions). The TI, therefore, indicates if the Teratogenic effects occur already at significantly lower concentrations compared to the Lethal effects.

A high TI number indicates that there are already Teratogenic effects although the concentrations remain significantly lower compared to the lethal concentrations.

In which two ways can a toxicant thave effect on the sexual characteristics?

1. Male organisms can adopt female characteristics. E.g. Endocrine-disrupting chemicals mimic estrogen and therefore stimulate female characteristics (e.g. Productions of egg cells).

2. Female organisms can adopt male characteristics. E.g. Whelks develop the male genitals in case of exposure to TBT.

In which 5 ways can toxins affect animals physiologically and in which 4 ways can toxins affect plants physically?

Animals
1. (Swimming) speed or stamina
2. Respiration
3. Excretion
4. Osmoregulation
5. Food conversion efficiency

Plants:
1. Stomatal function
2. Root growth
3. Respiration and Transpiration
4. Photosynthesis

Which 2 methods can be used to determine if a species is physiologically affected and what do they entail?

1. Scope of activity:
Here the different rates of oxygen consumption under maximum and minimum activity levels are measured.

2. Scope of growth:
Amount of energy uptaken by the species which is food - respiration - excretion (P = A - R -U)

In which three ways can de behavior of a species be affected?

1. Reproductive behavior changes (Less interest in reprodcution)

2. Prey animals are less aware about predators
3. Predators prey less on prey.

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