Chemical Mechanisms in Enzyme Catalysis - Chemical Mechanisms for Transition State Stabilization - Covalent catalysis
6 important questions on Chemical Mechanisms in Enzyme Catalysis - Chemical Mechanisms for Transition State Stabilization - Covalent catalysis
What happens with covalent catalysis?
What are the 2 states in covalent catalysis?
What 2 forms of covalent catalysis are there?
Electrophilic catalysis
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What is nucleophilic catalysis?
On what depends the strangest of a nucleophilic reaction?
Nucleus that donates the most at pH 7 is the best.
So: +nucleophilicity --> + covalent bond --> + enzyme activity
What is electrophilic catalysis?
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