Introductie in de exercise physiology
11 important questions on Introductie in de exercise physiology
How are muscle cells stimulated to start transcription and translation?
- stretch sensitive Ca2+ channels
- mechanical sensors in integrins/dystroglycans
- NO channels
Which growth factors are Ca2+ reliant?
- IGF-1
- MGF
What kind of steroid does the muscle cell activate upon self activation?
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The ER proteins are different than cytoplasmic proteins... What makes them different?
What happens to the endoplasmatic reticulum when it cannot handle 'stress'?
How likely is apoptosis by a muscle cell?
What are the effects on IGF-1 and MGF and the differences in effect of eccentric, concentric and isometric contractions?
concentric: low IGF-1 mRNA, middle MGF mRNA
isometric: high IGF-1 mRNA, high MGF mRNA
high Calcium also increases IGF-1 mRNA
myostatin is most reduced after eccentric exercise
What is the effect of myostatin?
On which cells do MGF act?
What makes myostatin a potent therapeutical?
What is the effect of HGF?
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