Diagnosis and Management of Acute Respiratory Failure - Pathofysiology of Acute Respiratory Failure - Hypoxemia
6 important questions on Diagnosis and Management of Acute Respiratory Failure - Pathofysiology of Acute Respiratory Failure - Hypoxemia
What is the most common underlying physiologic abnormality in hypoxemic respiratory failure?
Causes of low V/Q mismatch. (3)
- Obstruction of distal airways
- Alveolar filling/ flooding (eg. ARDS)
- Atelectasis
(eg, pneumonia, aspiration, pulmonary edema).
What is a compensatory mechanism in low V/Q mismatch?
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What is an extreme V/Q mismatch?
Treatment:
- Oxygen therapy/ mechanical ventilation
- Treating the underlying cause (infection, obstruction)
- Reopening atelectatic lung zones (recruiting)
Causes of decreased diffusion of oxygen across the alveolocapillary membrane? (3)
- Interstitial edema
- Inflammation
- Fibrosis
What is the range of a normal P/F ratio?
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