Water soluble vitamins and health - Folate
20 important questions on Water soluble vitamins and health - Folate
What are folates form a chemical perspective?
What needs to happen to the folates in order to be absorbed.
So there are specific tanrport protiens that require energy to take up these folates.
What happens to the monoglutamet in the intestinal cells?
So first you cut them of en now you put them back on again.
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How is folates exported from the intestinal cells to the blood?
Because folate pumps do not transport folates with multiple glutamate groups, these forms are retained within the cell until being shortened.
In which form is folate transported to the tissues?
How are folates taken up in the target cells?
What is one of the most important functions of folates?
These reactions are required for many basal physiological functions, such as the conversion of amino acids, production of blood cells, regulation of the activity of genes, or synthesis of new DNA during cell division.
What is the active form of folate in the body?
What is a methyl donor?
Why is folate imported for rapedly growing cells?
Synthesis of DNA is especially important in rapidly-growing cells, such as red blood cells.
Folates are therefore essential for normal cell division and proper growth.
How is folate and cancer connected?
Evidence to date indicates that adequate intake of natural folates might reduce the risk of some forms of cancer.
However, high doses of supplemental folic acid are correlated with increased colon cancer risk in individuals with a history of colorectal adenomas, and increased prostate cancer risk in men.
How can you get a folate deficiency?
How do they diagnose folate deficiency's?
What are early symptomes of folate deficiency?
What are things you can get when you have severe folate deficiency?
Deficiency during pregnancy may result in premature birth, low infant birth weight and fetal growth retardation. In children, growth may be retarded and puberty delayed.
In what kind of products can folate be found?
Spinach, liver, yeast, asparagus, and Brussels sprouts are among the foods with the highest levels of folate.
What is the DRA of folate?
On what is the DRA dependend?
What is Spina Befida?
Why is it a concern that a lot of people eat extra folate trough fortified products?
- Extra folate may hide a deficiency of vitamin B12. Vitamin
B12 deficiency leads to anemia and can also cause damage to the nerves. High doses of folate can prevent the development of anemia caused by vitamin B12 deficiency but do not influence nerve damage. - Extra folate may influence risk of chronic diseases via so called epigenetic mechanisms (The attachment of methyl tags to the DNA can turn genes on or off, thereby affecting the function of the DNA and of cells)
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